The 1910-S Indian eagle has a mintage of 811,000 pieces, higher than all other San Francisco Mint coins of this denomination. However, it is apparent from those known that most were placed in circulation as this issue is frequently found in significantly lower grades. Most were melted long ago and only a tiny fraction of that mintage survive today. Like all other Indian eagles from the San Francisco Mint, the 1910-S is rare in any Mint State grade and is very rare in Choice Uncirculated or finer. A small number of Gem examples exist, but this is a major rarity at the MS-65 or finer level.

The example to the left was sold by Stack's Bowers Galleries in the August 2013 Chicago ANA Auction, where it realized $82,250.